When evaluating drug safety,the dosage that causes 50 percent of subjects to exhibit a specific adverse effect is known as the

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The dosage that causes 50 percent of subjects to exhibit a specific adverse effect is known as the median toxic dose. This is important in evaluating drug safety as it helps determine the maximum safe dose of a drug before it becomes toxic to the body. The therapeutic index (C) is the ratio of the median toxic dose to the median effective dose and is used to assess the relative safety of a drug. The median therapeutic dose (A) is the dosage that produces a therapeutic effect in 50 percent of subjects, while the threshold dose (E) is the minimum dose required to produce a detectable effect. The ceiling effect (D) is the point at which increasing the dose of a drug no longer produces a greater response.

When Evaluating Drug Safety,the Dosage That Causes 50 Percent of Subjects