Prolonged,large doses of parathyroid hormone ______ bone breakdown,and small,intermittent amounts of parathyroid hormone ______ bone synthesis and remodeling.

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Prolonged, large doses of parathyroid hormone increase bone breakdown, while small, intermittent amounts of parathyroid hormone increase bone synthesis and remodeling. This dual effect is due to the hormone's different actions depending on its concentration and exposure time.

Prolonged,large Doses of Parathyroid Hormone ______ Bone Breakdown,and Small,intermittent Amounts