Capsaicin rubs,Tiger balm,and other salves used by athletes to soothe muscle injuries create a burning sensation.This sensation is likely due to the fact that the skin receptors they affect signal the release of _____,which eventually prevents the affected neurons from transmitting pain signals.

Question

Quizplus · Accepted Answer

Capsaicin and similar salves work by binding to a receptor on the skin called TRPV1, which causes the release of substance P. Substance P is a neuropeptide that transmits pain signals, and when it is depleted from the affected neurons, there is less pain perception. Endorphins, GABA, and cholecystokinins are not directly involved in this mechanism.

Capsaicin Rubs,Tiger Balm,and Other Salves Used by Athletes to Soothe