What evidence suggests that the NMDA receptor is responsible for associative learning?
A) NMDA activates only in long-term potentiated neurons.
B) Only multiple neurons firing simultaneously can activate the NMDA receptor.
C) Only glutamate can activate NMDA receptors.
D) Only high-frequency firing can activate NMDA receptors to cause long-term potentiation.

Question

Quizplus · Accepted Answer

The NMDA receptor requires simultaneous presynaptic glutamate release and postsynaptic depolarization, which typically occurs when multiple neurons fire together, a key mechanism in associative learning.

What Evidence Suggests That the NMDA Receptor Is Responsible for Associative