Which Combination of Factors Account for the Powhatans´ Failure to Stem

Which combination of factors account for the Powhatans´ failure to stem the tide of English expansion around the James River?

A) The devastation of Old World diseases, a lack of unity among Indian tribes compared to the tight-knit, militarily disciplined English settlers, and the English view of the Indians as economic obstacles, rather than assets, in their quest for land
B) The deadly spread of malaria, the English desire to take over Indian gold mines, and the unstinting hostility of the Powhatan Indians towards the English
C) The failure of the English to find gold on Indian land, the hatred of John Rolfe for the Indians, and the spread of smallpox
D) The similarity of the Indians and the Irish in Lord De La Warr´s eyes, the susceptibility of the Indians to smallpox and measles, and the paucity of natural resources in the area
E) The Indians´ inability to understand the value to the English of the abundant gold deposits in the area, the Indians´ willingness to let the English settlers take their land, and the devastation of diseases like measles and smallpox