Which of the following is thought to be the primary mechanism of action of negative-pressure wound therapy (NPWT) for wound healing?

Question

Quizplus · Accepted Answer

Microdeformation of cells is thought to be the primary mechanism of action of NPWT, as the negative pressure applied to the wound bed causes mechanical stretching and deformation of cells, which can promote cell proliferation and migration and ultimately accelerate wound healing. While NPWT may also have secondary effects such as increased blood flow and bacteriocidal effects, these are not thought to be the primary mechanisms of action. Facilitation of fibrinolysis is not a known mechanism of NPWT.

Which of the Following Is Thought to Be the Primary