There are several toxins that interfere with synaptic transmission. Botulism toxin, for example, interferes with the fusion of acetylcholine-containing vesicles with the membrane of the axon bulb. This would result in which one of the following?
A) blockage of Ca²⁺ diffusion into the axon
B) slow diffusion of the neurotransmitter across the synaptic cleft
C) inability of neurotransmitter to bind the receptor on the postsynaptic membrane
D) blocking of neurotransmitter release by the presynaptic membrane
E) hyperpolarization of the postsynaptic membrane

Question

Quizplus · Accepted Answer

Botulism toxin prevents the release of acetylcholine by inhibiting the fusion of vesicles with the presynaptic membrane, thus blocking neurotransmitter release.

There Are Several Toxins That Interfere with Synaptic Transmission