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The Hypothalamic-Pituitary-Adrenal (HPA) Axis Is an Important Hormonal Response System

Question 5

Multiple Choice

The hypothalamic-pituitary-adrenal (HPA) axis is an important hormonal response system in stress. Which of the following statements about the HPA axis is FALSE?


A) The response to stress involves the hypothalamic release of corticotropin-releasing hormone/factor, pituitary release of adrenocorticotropic hormone and adrenal release of cortisol.
B) Through the HPA axis, cortisol prepares the body for a fight-or-flight response by releasing glucose into the bloodstream, supplying an immediate energy source for muscle.
C) The HPA axis is subject to positive and negative feedbacks from circulating cortisol in order to restore systemic homeostasis.
D) After exposure to chronic stress, dysregulation of the HPA axis can occur and result in increased energy intake and altered macronutrient selection, towards more high fat and high sugar foods.
E) Responses to stress do not require adrenergic responses via the sympathetic nervous system and adrenal medulla as well as the HPA axis.

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