The difference between pathologic jaundice and physiologic jaundice is that pathologic jaundice:

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Nonphysiologic jaundice appears during the first 24 hours of life, whereas physiologic jaundice appears after the first 24 hours of life. Pathologic jaundice may lead to kernicterus, but it needs to be stopped before that occurs. Jaundice proceeds from the head down. Both jaundices are the result of the breakdown of erythrocytes. Pathologic jaundice is caused by a pathologic condition, such as Rh incompatibility.

The Difference Between Pathologic Jaundice and Physiologic Jaundice Is That