When a drug acts through non-competitive inhibition of an enzyme,it:

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Non-competitive inhibition occurs when the inhibitor binds to a site on the enzyme that is not the active site, called the allosteric site. This causes a change in the shape of the enzyme that prevents it from functioning properly. Since the inhibitor is not competing with the enzyme substrate for the active site, giving more substrate cannot overcome the inhibition. Non-competitive inhibition is usually reversible, and it does not necessarily mean that the drug is lethal to the person receiving treatment.

When a Drug Acts Through Non-Competitive Inhibition of an Enzyme,it