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What Is the Rationale for Giving Levodopa and Carbidopa as Combination

Question 7

Multiple Choice

What is the rationale for giving levodopa and carbidopa as combination therapy for Parkinson's disease?


A) Levodopa increases the therapeutic effect of carbidopa.
B) Carbidopa inhibits the breakdown of levodopa, increasing distribution to the central nervous system.
C) Both preparations are required to increase the availability of dopamine in the peripheries.
D) Levodopa increases the half-life of carbidopa.

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