Clients on atorvastatin should avoid ________ during therapy because it may increase the amount of atorvastatin in their circulation and therefore increase the chances of adverse effects occurring.

Question

Quizplus · Accepted Answer

Grapefruit juice inhibits the enzyme CYP3A4, responsible for the metabolism of atorvastatin. When this enzyme is inhibited, it can increase blood levels of atorvastatin, leading to an increased risk of adverse effects. Therefore, clients on atorvastatin should avoid grapefruit juice during therapy.

Clients on Atorvastatin Should Avoid ________ During Therapy Because It