The ventricular enlargement observed in clients with schizophrenia is most often accompanied by

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Ventricular enlargement in clients with schizophrenia is most often accompanied by cortical atrophy, which refers to shrinkage or loss of brain tissue in the cortex, the outermost layer of the brain that is involved in various cognitive and sensory functions. This is thought to be a consequence of neurodegenerative processes, chronic inflammation, oxidative stress, or impaired neuroplasticity in schizophrenia. Hypothalamic dysfunction, pituitary deformities, and thalamus abnormalities are not typically associated with ventricular enlargement in this disorder.

The Ventricular Enlargement Observed in Clients with Schizophrenia Is Most