Thalassemias are hemoglobin disorders in which the production of alpha and beta chains are out of balance.

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Thalassemias are caused by mutations in the genes that control the production of alpha and beta globins, which are the two types of protein chains that make up hemoglobin. In thalassemia, the balance between the production of these two chains is disrupted, resulting in abnormal hemoglobin and a range of symptoms including anemia, fatigue, weakness, and other complications.

Thalassemias Are Hemoglobin Disorders in Which the Production of Alpha