Amyloid deposited in the tissue of patients who are on dialysis for chronic renal failure is most often biochemically related to which precursor protein?
A) Light chain of immunoglobulin G
B) Serum amyloid associated (SAA) protein
C) Transthyretin
D) ß2-microglobulin
E) Calcitonin

Question

Quizplus · Accepted Answer

ß₂-microglobulin is a component of the major histocompatibility complex on the cell surface and is also normally present in deposits in the tissues of patients on long-term hemodialysis, forming amyloid fibrils.

Amyloid Deposited in the Tissue of Patients Who Are on Dialysis