A 15-year-old boy developed generalized lymphadenopathy, accompanied by fever and malaise. A lymph node biopsy specimen showed that the architecture of the lymph nodes was erased and the nodes were infiltrated with moderately large lymphoid cells. There were numerous mitoses and apoptotic bodies. Between the B lymphocytes, there were phagocytic macrophages, imparting a "starry-sky" appearance to the lymph node. Which of the following is the most likely diagnosis?

Question

Quizplus · Accepted Answer

Burkitt lymphoma presents with diffuse infiltration of the lymph nodes. There are many mitoses, apoptotic bodies, and macrophages that impart a starry-sky appearance to the lymph node.

A 15-Year-Old Boy Developed Generalized Lymphadenopathy, Accompanied by Fever and Malaise