This liver tumor nodule, measuring 6 cm in diameter, was seen on a computerized tomography (CT) scan of a 40-year-old man. Initially, the nodule was considered to be benign, but when it became painful, the patient decided to have it removed. Histologically, it was composed of well-differentiated hepatocytes, whereas the central scar and the fibrous septa contained proliferating bile ducts. This nodule is most likely

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This nodule represents focal nodular hyperplasia (FNH), a lesion considered to be neither a benign nor a malignant tumor nor a hamartoma. FNH lesions are hepatocellular nodules arranged around a central fibrous scar. In contrast to hepatocellular adenomas, which are composed exclusively of liver cells, FNH contains fibrous tissue and bile ducts. In contrast to liver cell carcinoma, FNH is composed of normal, non-neoplastic liver cells.

This Liver Tumor Nodule, Measuring 6 Cm in Diameter, Was