A high level of expression of the tumor suppressor gene PTEN will most likely be found in which of the following?

Question

Quizplus · Accepted Answer

The tumor suppressor gene PTEN is normally expressed in the endometrial glands in the proliferative phase of the menstrual cycle, but it is not expressed in the secretory phase. It is also lost in 63% of premalignant complex atypical endometrial hyperplasia (also known as endometrial intraepithelial neoplasia) and in 50%-80% of endometrial adenocarcinomas.

A High Level of Expression of the Tumor Suppressor Gene