Macrophages and neutrophils express several enzymes that are involved in biochemical mechanisms that kill ingested microbes.Which of the following is NOT an enzyme expressed by these cells?
A)Inducible nitric oxide synthase (iNOS)
B)Granzyme B
C)Phagocyte oxidase
D)Myeloperoxidase
E)Lysozyme

Question

Quizplus · Accepted Answer

Granzyme B,a proteolytic enzyme component of cytolytic T lymphocyte (CTL)and natural killer (NK)cell granules,is involved in initiating caspase-dependent CTL killing of target cells.Granzyme B is not involved in phagocyte killing of ingested microbes.Inducible nitric oxide synthase (iNOS)generates NO in macrophages,and NO is toxic to microbes.Phagocyte oxidase and myeloperoxidase are involved in generating free radical species that kill ingested microbes in phagocytes.Lysozyme is a proteolytic enzyme in neutrophil granules that contributes to microbial killing.

Macrophages and Neutrophils Express Several Enzymes That Are Involved in Biochemical