Which one of the following statements about MHC-TCR interactions is NOT true?
A) Antigen receptors on T cells bind to MHC molecules for only brief periods of time.
B) The affinity of most TCRs for peptide-MHC complexes is similar to the affinity of antibodies for their antigens.
C) Only 1% or less of the MHC molecules on any antigen-presenting cell (APC) display a peptide recognized by a particular T cell.
D) T cells usually require multiple engagements with an APC before a threshold of activation is reached.
E) A subthreshold number of MHC-TCR interactions can lead to T cell inactivation.
Correct Answer:
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