Many tumors are found to overexpress bcl-2,which favors survival of the transformed cells.Which of the following best describes the function of bcl-2?
A) Direct inhibition of caspase-8
B) Direct inhibition of caspase-9
C) Up-regulates expression of DNA repair enzymes
D) Reduces the leakiness of the mitochondrial membrane
E) Inhibits the activity of granzymes released from cytotoxic T lymphocytes
Correct Answer:
Verified
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