Which of the following factors generally favors stimulation of an adaptive immune response to an antigen,and not tolerance?
A)Intravenous portal of entry of antigen
B)Presence of antigen in generative lymphoid organs
C)Absence of costimulatory molecules on antigen-presenting cells
D)Innate immune response to the antigen
E)Presence of antigen during the neonatal period

Question

Quizplus · Accepted Answer

Innate immune responses enhance the ability of antigen to activate naive B cells and T cells in various ways,such as by inducing costimulatory molecules on the antigen-presenting cells.The presence of antigen within generative lymphoid organs (bone marrow,thymus)favors central tolerance.Neonatal exposure to antigen favors neonatal tolerance.Both intravenous administration of antigen and lack of costimulators favor peripheral tolerance.

Which of the Following Factors Generally Favors Stimulation of an Adaptive