Orofacial clefts are one of the most common craniofacial congenital defects. The presence of an orofacial cleft most likely indicates the presence of a syndrome.

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Orofacial clefts are one of the most common craniofacial congenital defects because they affect nearly 7,000 births annually. The presence of an orofacial cleft is most strongly associated with other factors since clefts associated with syndromes are rare.

Orofacial Clefts Are One of the Most Common Craniofacial Congenital