For each of the descriptions in questions , choose the T cell signaling molecule that best matches it from the list below (A-O).
-Immunosuppressive therapy with the drugs cyclosporine and FK506 inhibits T cell activation by blocking the protein phosphatase activity of this molecule.
A)CD3
B)Lck
C)Zap-70
D)LAT
E)Ras
F)PLCγ
G)PIP2
H)PIP3
I)IP3
J)DAG
K)Calcineurin
L)NFAT
M)Jun
N)Fos
O)NF-γB

Question

Quizplus · Accepted Answer

Calcineurin is responsible for the dephosphorylation of NFAT, which is an essential transcription factor for the activation of T and B cells
The immunosuppressive drugs cyclosporine and FK506 function by inhibiting calcineurin
These drugs are commonly used to prevent transplant rejection.

For Each of the Descriptions in Questions , Choose the T