Buddha believes that the root cause of all suffering (dukkha) is desire.

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According to Buddhist philosophy, desire (tanha) is the root cause of suffering. The more one desires, the more attached they become to their desires and the more suffering they will experience when these desires are unfulfilled or temporary. By eliminating desire, one can attain Nirvana or the ultimate state of enlightenment and freedom from suffering.

Buddha Believes That the Root Cause of All Suffering (Dukkha)