Select the True Statements

Select the true statements.

A) If a compound with a single asymmetric carbon has the S configuration, it has levorotatory optical activity.
B) Any compound with one asymmetric carbon is chiral.
C) Meso compounds are chiral.
D) For any reaction that does not affect the bonds to an asymmetric carbon, if the configuration of this carbon is R, the products must also have the R configuration at this carbon.
E) A compound X with four asymmetric carbons is the enantiomer of a compound Y. Compound X must then have a diastereomer Z.