DNA polymerase is an enzyme that catalyzes the nucleophilic attack of a 3ʹ-OH group of a deoxyribose sugar on the alpha-phosphorus of another nucleoside triphosphate. Draw a curved-arrow mechanism showing this attack, then identify the leaving group lost and what the driving force of the reaction is.

Question

DNA polymerase is an enzyme that catalyzes the nucleophilic attack of a 3ʹ-OH group of a deoxyribose sugar on the alpha-phosphorus of another nucleoside triphosphate. Draw a curved-arrow mechanism showing this attack, then identify the leaving group lost and what the driving force of the reaction is.
DNA polymerase is an enzyme that catalyzes the nucleophilic attack of a 3ʹ-OH group of a deoxyribose sugar on the alpha-phosphorus of another nucleoside triphosphate. Draw a curved-arrow mechanism showing this attack, then identify the leaving group lost and what the driving force of the reaction is.

Quizplus · Accepted Answer

The Answer of DNA polymerase is an enzyme that catalyzes the nucleophilic attack of a 3ʹ-OH group of a deoxyribose sugar on the alpha-phosphorus of another nucleoside triphosphate. Draw a curved-arrow mechanism showing this attack, then identify the leaving group lost and what the driving force of the reaction is.

DNA Polymerase Is an Enzyme That Catalyzes the Nucleophilic Attack