The therapy that most directly improves cardiac contractility in a patient with systolic heart failure is

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Digitalis may be used for symptom management of heart failure.Cardiac glycosides directly inhibit the sodium-potassium pump present in the cell membrane of all cells.The intracellular changes allow more calcium to remain in the cell,thus strengthening myocardial contraction.Contractility is not improved through afterload reduction.Beta-blockers inhibit the effects of sympathetic activation and have the potential to reduce cardiac output.Preload reduction is not the therapy of choice in improving cardiac contractility.

The Therapy That Most Directly Improves Cardiac Contractility in a Patient