A Female Infertility Patient Is Found to Be Hypoestrogenic at the PreChapterual

A female infertility patient is found to be hypoestrogenic at the preChapterual clinic visit. She asks the nurse why she has never been able to get pregnant. Which response is best?

A) Circulating estrogen contributes to secondary sex characteristics.
B) Estrogen deficiency prevents the ovum from reaching the uterus and may be a factor in infertility.
C) Hyperestrogen may be preventing the zona pellucida from forming an ovum protective layer.
D) The corona radiata is preventing fertilization of the ovum.