A major pathway that signals cell survival and inhibits cell death is the _______ pathway.

Question

Quizplus · Accepted Answer

The PI 3-kinase/Akt pathway is a major pathway that signals cell survival and inhibits cell death by promoting cell proliferation and inhibiting apoptotic cell death. The pathway is activated by growth factor receptors and leads to the phosphorylation and activation of Akt, which phosphorylates and inhibits pro-apoptotic proteins. The other pathways listed (Hedgehog, TNF, and Wnt) are involved in various cellular processes but are not directly associated with cell survival and inhibition of cell death.

A Major Pathway That Signals Cell Survival and Inhibits Cell