Skin fibroblasts near a wound, arrested in G₀,are stimulated to enter G₁ by _______ growth factor.

Question

Quizplus · Accepted Answer

Platelet-derived growth factor (PDGF) is known to stimulate the migration and proliferation of fibroblasts near a wound, leading to the formation of new connective tissue and eventual wound healing. Epidermal growth factor (EGF) is involved in the proliferation and differentiation of epithelial cells, while fibroblast growth factor (FGF) is involved in the proliferation and differentiation of multiple cell types. Keratinocyte growth factor (KGF) specifically stimulates the proliferation and differentiation of epithelial cells, particularly those of the skin and hair. While all of these growth factors may play a role in wound healing, PDGF is the most specific to fibroblast activation and migration.

Skin Fibroblasts near a Wound, Arrested in G0, are Stimulated

Skin Fibroblasts near a Wound, Arrested in G₀,are Stimulated