Cdks bind to cyclin and are activated by
A) phosphorylation by Wee1.
B) dephosphorylation by Cdc25 protein phosphatase.
C) the binding of Ink4.
D) the binding of Cip.

Question

Quizplus · Accepted Answer

Cdks are activated by dephosphorylation by Cdc25 protein phosphatase. Cyclin binding alone is not enough to activate Cdks, but it is necessary for their activity. The binding of Ink4 and Cip are both examples of inhibitors of Cdks, not activators. Phosphorylation by Wee1 is also a regulatory mechanism for Cdks, but it inhibits their activity rather than activating them.

Cdks Bind to Cyclin and Are Activated by