To prevent cells with unreplicated DNA from passing through the G₂ checkpoint, Chk1 and Chk2 _______ protein phosphatase Cdc25. A) phosphorylate and stimulate B) phosphorylate and inhibit C) dephosphorylate and stimulate D) dephosphorylate and induce the degradation of

Question

Quizplus · Accepted Answer

Chk1 and Chk2 phosphorylate and inhibit protein phosphatase Cdc25, which in turn prevents the activation of cyclin-dependent kinases and blocks the progression of the cell cycle at the G₂ checkpoint until DNA replication is completed.

To Prevent Cells with Unreplicated DNA from Passing Through the G2

To Prevent Cells with Unreplicated DNA from Passing Through the G₂