The beginning of anaphase occurs when cohesins, holding the sister chromatids together, are degraded by
A) anaphase-promoting complex.
B) ATM.
C) proteasome.
D) separase.

Question

Quizplus · Accepted Answer

The beginning of anaphase occurs when cohesins, holding the sister chromatids together, are degraded by separase, an enzyme that cleaves the cohesin protein complexes. Option A is incorrect because the anaphase-promoting complex is involved in degrading proteins that regulate the progression of the cell cycle, but not specifically targeting cohesins. Option B is incorrect because ATM is a protein kinase involved in detecting DNA damage and signaling cell cycle arrest, but not involved in degrading cohesins. Option C is incorrect because the proteasome is a protein complex that degrades proteins targeted for destruction, but not specifically targeting cohesins in sister chromatids.

The Beginning of Anaphase Occurs When Cohesins, Holding the Sister