Integrins bind to
A) collagen, laminin, and fibronectin.
B) plectin and proteoglycans.
C) α-actinin, vinculin, and talin.
D) All of the above

Question

Quizplus · Accepted Answer

Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion. They bind to various ECM proteins including collagen, laminin, and fibronectin, as well as to cell adhesion molecules within the cell such as α-actinin, vinculin, and talin, which link integrins to the actin cytoskeleton. Plectin and proteoglycans are also associated with the cell matrix and cytoskeleton, indicating that integrins have a broad range of binding partners, encompassing all the options listed.

Integrins Bind to