The major cell surface receptor(s) responsible for the attachment of cells to the extracellular matrix is(are)

Question

Quizplus · Accepted Answer

Integrins are the major cell surface receptors responsible for attaching cells to the extracellular matrix. Integrins bind to proteins such as fibronectin, laminin, and collagen, which make up the extracellular matrix. Hemidesmosomes and desmosomes are types of junctions that anchor cells to each other, but not to the extracellular matrix directly. Laminin is a protein found in the extracellular matrix that can bind to integrins on cell surfaces.

The Major Cell Surface Receptor(s) Responsible for the Attachment of Cells