A major function of tight junctions is to
A) create strong cell-cell adherence.
B) promote the intermixing of proteins between the apical and basolateral surfaces of cells.
C) seal the space between adjacent cells to provide, for example, a barrier to glucose diffusion across an epithelial cell layer.
D) sort cells on the basis of adhesion during cell migration in embryos.

Question

Quizplus · Accepted Answer

Tight junctions are specialized structures that seal the space between adjacent cells, forming a barrier that regulates the movement of ions and molecules across epithelial tissues. This function is important in maintaining the polarity of the cell membrane and in preventing the uncontrolled diffusion of substances across the barrier. Tight junctions also help to prevent the loss of extracellular fluid from tissues and serve as a structural support for epithelial cells.

A Major Function of Tight Junctions Is to