Gene therapy for cystic fibrosis involves transfer of the _______ gene into bronchial epithelia.

Question

Quizplus · Accepted Answer

Cystic fibrosis is caused by a mutation in the CFTR gene, which encodes for a chloride ion channel in the epithelial cells of the lungs, pancreas, and other organs. Gene therapy aims to introduce a functional CFTR gene into these cells to restore chloride ion transport and improve mucus clearance. Therefore, choice A (CFTR) is the correct answer. Choices B, C, and D are not involved in the pathogenesis of cystic fibrosis.

Gene Therapy for Cystic Fibrosis Involves Transfer of the _______