The human mitochondrial genome encodes only 22 tRNAs. This limited array of tRNAs can read the 64 possible triplet codons through extreme wobble in base pairing at the third codon position and the use of a(n) _______ genetic code.

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The term "nonuniversal mitochondrial" refers to the fact that the genetic code used by mitochondrial genomes differs from the universal genetic code used by nuclear genomes and most other organisms. Mitochondria have their own set of tRNAs and codons, and the wobble base pairing and other adaptations in the mitochondrial genetic code allow for the limited number of tRNAs to read all 64 codons.

The Human Mitochondrial Genome Encodes Only 22 TRNAs