If secretory proteins are isolated from secretory vesicles and injected into the cytosol, they will

Question

Quizplus · Accepted Answer

Secretory proteins are destined for secretion and are therefore synthesized and sorted into secretory vesicles. If these proteins are injected into the cytosol, they will not have the necessary signal sequences to be recognized by the translocation machinery of the rough ER and will remain in the cytosol. Without the proper sorting signals, they will not be taken up into secretory vesicles and will not be secreted. Instead, they will likely be degraded within the cytosol by various degradation pathways.

If Secretory Proteins Are Isolated from Secretory Vesicles and Injected