Gaucher disease results from the failure of macrophage lysosomes to hydrolyze
A) proteins.
B) glycolipids.
C) DNA.
D) polysaccharides.

Question

Quizplus · Accepted Answer

Gaucher disease is a lysosomal storage disorder caused by a deficiency of the enzyme glucocerebrosidase, which results in the accumulation of glycolipids, particularly glucocerebroside, in cells of the reticuloendothelial system (mainly macrophages). This leads to the enlargement of spleen and liver, destruction of bone tissue, anemia, low platelet counts, and easy bruising and bleeding.

Gaucher Disease Results from the Failure of Macrophage Lysosomes to Hydrolyze