Cancer cells repress some genes that are expressed in normal cells. Suppose you wanted to design two drugs to treat cancer cells. Which activities would you want your drugs to have?

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B) DNA demethylase activity and histone acetyltransferase activity. These activities would promote gene expression by removing methyl groups from DNA, making it less compact and more accessible for transcription, and by adding acetyl groups to histones, which also leads to a more open chromatin structure and facilitates gene expression. This could counteract the repression of genes in cancer cells.

Cancer Cells Repress Some Genes That Are Expressed in Normal