In the 1960s, scientists discovered that acetylation of histones was correlated with increased transcription of chromatin. However, it took another 30 years before evidence was found that allowed scientists to say that acetylation was directly responsible for activating regions of chromatin for transcription. What was this evidence, and why did it provide a direct link between histone acetylation and gene activation?

Question

Quizplus · Accepted Answer

The Answer of In the 1960s, scientists discovered that acetylation of histones was correlated with increased transcription of chromatin. However, it took another 30 years before evidence was found that allowed scientists to say that acetylation was directly responsible for activating regions of chromatin for transcription. What was this evidence, and why did it provide a direct link between histone acetylation and gene activation?

In the 1960s, Scientists Discovered That Acetylation of Histones Was