mRNAs are degraded in the cytoplasm by
A) shortening of the poly-A tail and degradation from the 3′ end by nucleases.
B) removal of the 5′ cap and degradation from the 5′ end by nucleases.
C) Both a and b
D) Neither a nor b

Question

Quizplus · Accepted Answer

mRNA degradation in the cytoplasm involves both shortening of the poly-A tail and degradation from the 3′ end by nucleases as well as removal of the 5′ cap and degradation from the 5′ end by nucleases. Both processes contribute to the eventual degradation of the mRNA molecule.

MRNAs Are Degraded in the Cytoplasm by