During replication, _______ stabilize the unwound DNA template so it can be copied by the DNA polymerase.
A) Single-stranded DNA-binding proteins
B) Helicases
C) PCNAs
D) Topoisomerases

Question

Quizplus · Accepted Answer

Single-stranded DNA-binding proteins bind to the single-stranded template DNA during replication and prevent it from re-forming a double-helical structure, stabilizing it for copying by DNA polymerase. Helicases unwind the double-stranded DNA at the replication fork. PCNAs (proliferating cell nuclear antigens) and topoisomerases also play roles in replication, but not in stabilizing the unwound template.

During Replication, _______ Stabilize the Unwound DNA Template So It