Consider two signaling pathways: A-B-C-D-E and 1-2-3-4-5-6-7.Which response would be representative of stimulatory crosstalk?
A) B stimulates E
B) B stimulates 6
C) D stimulates A
D) 2 stimulates 7

Question

Quizplus · Accepted Answer

Stimulatory crosstalk occurs when one signaling pathway enhances the activity of another pathway. In this case, pathway A-B-C-D-E and pathway 1-2-3-4-5-6-7 do not have any direct interaction, so options A and C can be eliminated. Option D suggests that pathway 2 stimulates pathway 7, but this is not necessarily a stimulatory crosstalk as pathway 2 may just be inhibiting pathway 7. Option B suggests that pathway B stimulates both E and 6, which is an example of stimulatory crosstalk as pathway B enhances the activity of both pathways D-E and 5-6. Therefore, option B is the best choice that represents stimulatory crosstalk.

Consider Two Signaling Pathways: A-B-C-D-E and 1-2-3-4-5-6-7