The most energetically favorable reactions in glycolysis are catalyzed in reverse in gluconeogenesis by
A) shifting their equilibrium.
B) the glycolytic enzymes using ATP.
C) the use of different enzymes coupled with energy from ATP or NADH.
D) accumulation of high substrate concentrations.

Question

Quizplus · Accepted Answer

Gluconeogenesis is the reverse pathway to glycolysis, therefore, the most energetically favorable reactions must be catalyzed in reverse. However, different enzymes are needed to perform the reverse reaction. Coupled with the energy from ATP or NADH, the reverse reaction can happen.

The Most Energetically Favorable Reactions in Glycolysis Are Catalyzed in Reverse