The first Greek philosophers to say there was no single best human way of life were:

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The Sophists were the first Greek philosophers to argue that there was no single best human way of life. They believed that truth and morality were relative, and that individuals must find their own way in the world. The Pythagoreans, Neoplatonists, and Aristotelians all believed in a more objective sense of morality and the existence of a single best human way of life.

The First Greek Philosophers to Say There Was No Single