What marked the 'fall' of Rome in 476 CE?

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The last Western emperor, Romulus Augustus, was deposed in 476 CE. While there were a number of factors that contributed to the decline of the Western Roman Empire, the end of the line for the Roman emperors in the west came when Odoacer, a Germanic warrior, overthrew Romulus Augustus and declared himself king of Italy. This event marked the end of the Roman Empire in the west and the beginning of the Middle Ages.

What Marked the 'Fall' of Rome in 476 CE