What was the most significant cause of decline in the population of Indians after the arrival of white Europeans in their area?

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Quizplus · Accepted Answer

The most significant cause of decline in the population of Indians was the diseases to which they had no immunity. The Europeans brought with them diseases such as smallpox, influenza, and measles that were devastating to the indigenous population, as they had no natural immunity to them. It is estimated that diseases caused the death of millions of indigenous people. Casualties of battles, loss of confidence in their ability to sustain their culture, and voluntary emigration certainly had an impact on the population, but not to the same extent as diseases.

What Was the Most Significant Cause of Decline in the Population